Maxime Delmas (🤝)

AI Researcher

About Me

I am currently a Postdoctoral Researcher at Idiap Research Institute, in the Neuro-symbolic AI Lab. My work focuses on Information Extraction, Retrieval-Augmented Generation (RAG), Knowledge Graphs and Knowledge Discovery, applied to the Biomedical domain.

After a PhD at INRAE (Toulouse, France) focused on Knowledge Graph applications in metabolomics, I joined the Neuro-Symbolic AI Lab at Idiap (Martigny, Switzerland) in 2022. Combining Knowledge Representation with Natural Language Processing (Information Extraction, RAG), I had the opportunity to apply my research to complex real-world challenges (Antibiotic discovery, Climate risk analysis). Now, I explore how AI methods and Knowledge Graphs can push the boundaries of scientific discovery, especially in the biomedical domain.

I believe in curiosity and collaboration as the core of a healthy work environment. To me, both intense work and informal conversations over a hot coffee (or tea), are the essential ingredients for great projects and breakthrough ideas.

"The whole is greater than the sum of its parts." To me, this has a broad and beautiful meaning. Across scales, from a single cell to entire ecosystems, and to us as a scientific community, interconnected systems naturally generate emergent properties that often exist implicitly, waiting to be revealed. This perspective drives my research: uncovering latent knowledge emerging from the vast landscape of scientific literature.

Experience

2022 - present

Postdoctoral Researcher

Idiap Research Institute, Martigny, Switzerland

  • Industry Project Lead MAVERICK (2024 - 2026): Developed a large-scale graph-augmented RAG system for complex, multi-faceted QA across heterogeneous corpora. In collaboration with Basinghall Analytics.
  • Industry Project Lead ABROAD (2022 - 2024): Designed an end-to-end hybrid Knowledge Graph–LLM platform for leveraging large-scale scientific literature to support decision-making in antibiotic discovery. In collaboration with Inflamalps.
2019 - 2022

PhD Student

INRAE ToxAlim, Toulouse, France

Developed FORUM, a large-scale Knowledge Graph integrating scientific literature, life science databases, and metabolic networks for hypothesis generation and predictions of disease biomarkers.

2017 - 2019

Apprenticeship (MSc in Bioinformatics)

UMR 5088 CNRS, Toulouse, France

Development of circular RNAs and very long intergenic non-coding RNAs detection workflows for analysis of RNA-Seq data.

Publications

2026

A Navigational Approach for Comprehensive RAG via Traversal over Proposition Graphs

Maxime Delmas, Lei Xu and André Freitas

arXiv Preprint

2025

Accelerating Antibiotic Discovery with Large Language Models and Knowledge Graphs

Maxime Delmas, Magdalena Wysocka, Danilo Gusicuma, and Andre Freitas

In Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics

2024

Relation extraction in underexplored biomedical domains: A diversity-optimized sampling and synthetic data generation approach

Maxime Delmas, Magdalena Wysocka and Andre Freitas

Computational Linguistics

An LLM-based Knowledge Synthesis and Scientific Reasoning Framework for Biomedical Discovery

Oskar Wysocki, Magdalena Wysocka, Danilo Carvalho, Alex Teodor Bogatu, Danilo Miranda Gusicuma, Maxime Delmas, Harriet Unsworth, Andre Freitas

In Proceedings of the 62nd Annual Meeting of the Association for Computational Linguistics

Genome scale metabolic network modelling for metabolic profile predictions

Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

PLOS Computational Biology

2023

Large Language Models, scientific knowledge and factuality: A framework to streamline human expert evaluation

Magdalena Wysocka, Oskar Wysocki, Maxime Delmas, Vincent Mutel, André Freitas

Journal of Biomedical Informatics

Suggesting disease associations for overlooked metabolites using literature from metabolic neighbors

Maxime Delmas, Olivier Filangi, Christophe Duperier, Nils Paulhe, Florence Vinson, Pablo Rodriguez-Mier, Franck Giacomoni, Fabien Jourdan, Clément Frainay

GigaScience

2021

FORUM: building a Knowledge Graph from public databases and scientific literature to extract associations between chemicals and diseases

Maxime Delmas, Olivier Filangi, Nils Paulhe, Florence Vinson, Christophe Duperier, William Garrier, Paul-Emeric Saunier, Yoann Pitarch, Fabien Jourdan, Franck Giacomoni, Clément Frainay

Bioinformatics

Circular ANRIL isoforms switch from repressors to activators of p15/CDKN2B expression during RAF1 oncogene-induced senescence

Lisa Muniz, Sandra Lazorthes, Maxime Delmas, Julien Ouvrard, Marion Aguirrebengoa, Didier Trouche, Estelle Nicolas

RNA Biology

Activities

Teaching

2025

Tutorial: Biomedical Knowledge Graphs meet LLM.

Basel Computational Biology Conference, Basel, Switzerland

2023

Summer School: Multi-omics Data Analysis, Integration and Results Contextualisation - An introduction to metabolic models, Semantic Web and Knowledge Graphs.

Aussois, France